Kevin J Tracey Selected Research

Choline O-Acetyltransferase (Choline Acetyltransferase)

10/2021	Systemic administration of choline acetyltransferase decreases blood pressure in murine hypertension.
1/2019	Choline acetyltransferase-expressing T cells are required to control chronic viral infection.
1/2017	Forebrain Cholinergic Dysfunction and Systemic and Brain Inflammation in Murine Sepsis Survivors.
3/2011	Cardiopulmonary arrest and resuscitation disrupts cholinergic anti-inflammatory processes: a role for cholinergic α7 nicotinic receptors.

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Kevin J Tracey Research Topics

Disease

106	Inflammation (Inflammations) 04/2022 - 03/2002
73	Sepsis (Septicemia) 01/2022 - 01/2002
35	Endotoxemia 01/2019 - 01/2002
32	Infections 11/2020 - 09/2002
15	Ischemia 01/2021 - 04/2002
11	Necrosis 01/2016 - 04/2002
10	Arthritis (Polyarthritis) 01/2021 - 12/2002
9	Shock 01/2018 - 03/2002
8	COVID-19 04/2022 - 01/2020
8	Pneumonia (Pneumonitis) 01/2020 - 01/2004
7	Acute Lung Injury 01/2020 - 01/2002
7	Lung Injury 01/2020 - 04/2003
7	Rheumatoid Arthritis 01/2019 - 03/2007
6	Neoplasms (Cancer) 11/2021 - 04/2005
6	Autoimmune Diseases (Autoimmune Disease) 01/2021 - 02/2012
6	Body Weight (Weight, Body) 01/2021 - 02/2005
6	Hemorrhagic Shock 11/2013 - 09/2002
6	Brain Ischemia (Cerebral Ischemia) 03/2011 - 04/2002
5	Reperfusion Injury 01/2018 - 12/2002
5	Wounds and Injuries (Trauma) 02/2017 - 06/2002
5	Hemorrhage 11/2013 - 02/2005
5	Fever (Fevers) 06/2010 - 12/2003
4	Cytokine Release Syndrome 04/2022 - 09/2020
4	Insulin Resistance 01/2021 - 01/2011
4	Neuroinflammatory Diseases 01/2017 - 03/2011
4	Experimental Arthritis 01/2016 - 08/2004
4	Atherosclerosis 05/2011 - 03/2007
4	Anorexia 06/2010 - 05/2002
4	Peritonitis 06/2010 - 05/2003
3	Disease Progression 04/2022 - 11/2019
3	Chronic Disease (Chronic Diseases) 01/2022 - 12/2015
3	Multiple Organ Failure (MODS) 01/2022 - 09/2005
3	Septic Shock (Toxic Shock Syndrome) 01/2022 - 01/2004
3	Pain (Aches) 11/2021 - 01/2021
3	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2021 - 01/2011
3	Alzheimer Disease (Alzheimer's Disease) 01/2021 - 02/2015
3	Hyperalgesia 01/2021 - 12/2001
3	Hyperglycemia 01/2019 - 11/2015
3	Obesity 12/2012 - 01/2011
3	Hypotension (Low Blood Pressure) 06/2010 - 05/2003

Drug/Important Bio-Agent (IBA)

98	HMGB1 Protein (HMG1)IBA 01/2022 - 01/2002
74	CytokinesIBA 01/2022 - 05/2002
37	Proteins (Proteins, Gene)FDA Link 01/2022 - 04/2002
25	EndotoxinsIBA 10/2018 - 03/2002
22	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2020 - 03/2002
18	Cholinergic Agents (Cholinergics)IBA 01/2022 - 03/2002
16	AntibodiesIBA 01/2022 - 01/2002
10	Interleukin-6 (Interleukin 6)IBA 01/2017 - 05/2002
9	Receptor for Advanced Glycation End ProductsIBA 11/2019 - 10/2005
7	LipopolysaccharidesIBA 04/2022 - 09/2005
7	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 04/2022 - 05/2006
6	Galantamine (Galanthamine)FDA LinkGeneric 01/2021 - 01/2009
6	InterleukinsIBA 11/2019 - 01/2006
6	LigandsIBA 01/2018 - 10/2005
5	Cholinesterase Inhibitors (Anticholinesterases)IBA 01/2021 - 01/2009
5	CaspasesIBA 11/2019 - 04/2003
5	Acetylcholine (Acetylcholine Chloride)FDA Link 01/2019 - 11/2004
5	EnzymesIBA 01/2019 - 04/2002
5	InflammasomesIBA 01/2018 - 10/2010
5	DNA (Deoxyribonucleic Acid)IBA 01/2014 - 01/2004
5	Nicotine FDA Link 01/2007 - 11/2004
4	Famotidine (Pepcid)FDA LinkGeneric 04/2022 - 01/2020
4	Choline O-Acetyltransferase (Choline Acetyltransferase)IBA 10/2021 - 03/2011
4	Pharmaceutical PreparationsIBA 01/2021 - 10/2005
4	AdipokinesIBA 01/2021 - 01/2011
4	Monoclonal AntibodiesIBA 01/2020 - 12/2013
4	3-(2,4-dimethoxybenzylidene)anabaseineIBA 01/2020 - 05/2006
4	ethyl pyruvateIBA 01/2018 - 09/2002
4	Insulin (Novolin)FDA Link 07/2017 - 11/2015
4	Biological ProductsIBA 02/2017 - 04/2005
4	Messenger RNA (mRNA)IBA 12/2016 - 11/2008
4	Hemoglobins (Hemoglobin)IBA 05/2016 - 06/2002
4	Neutralizing AntibodiesIBA 01/2016 - 12/2002
4	alpha7 Nicotinic Acetylcholine ReceptorIBA 09/2008 - 01/2003
3	Toll-Like Receptor 4IBA 11/2021 - 12/2015
3	DisulfidesIBA 11/2021 - 03/2012
3	LipidsIBA 01/2021 - 02/2004
3	salicylhydroxamic acid (SHAM)IBA 01/2021 - 03/2002
3	Immunoglobulin G (IgG)IBA 01/2021 - 01/2004
3	Biomarkers (Surrogate Marker)IBA 11/2019 - 07/2009
3	Peptides (Polypeptides)IBA 01/2019 - 02/2005
3	Adenosine Triphosphate (ATP)IBA 01/2019 - 09/2010
3	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2018 - 05/2007
3	Interleukin-10 (Interleukin 10)IBA 01/2017 - 02/2005
3	AcetylcholinesteraseIBA 01/2017 - 01/2009
3	Neurotransmitter Agents (Neurotransmitter)IBA 12/2016 - 11/2008
3	Cholinergic ReceptorsIBA 11/2015 - 04/2007
3	Pathogen-Associated Molecular Pattern MoleculesIBA 01/2015 - 07/2009
3	DNA-Binding Proteins (DNA Binding Protein)IBA 01/2014 - 01/2003
3	Nuclear Proteins (Protein, Nuclear)IBA 11/2009 - 04/2003
3	Anti-Bacterial Agents (Antibiotics)IBA 01/2007 - 01/2004
3	Interleukin-1 (Interleukin 1)IBA 02/2006 - 06/2003

Therapy/Procedure

22	Therapeutics 01/2022 - 01/2003
14	Vagus Nerve Stimulation 03/2022 - 01/2003
12	Ligation 11/2019 - 11/2005
12	Punctures 11/2019 - 11/2005
5	Critical Care (Surgical Intensive Care) 12/2016 - 01/2004
4	Vagotomy 01/2019 - 03/2002
4	Resuscitation 03/2011 - 02/2005
3	Intraperitoneal Injections 06/2010 - 06/2005